ANGES: reconstructing ANcestral GEnomeS maps

This page contains the software ANGES 1.01, that aims at reconstucting ancestral genome maps from homologous markers in extant related genomes.

Download

• Program, version 1.01 (July 10, 2012, documentation updated in August 2014)
• Examples with results (featured ancestors: boreoeutherian, amniote, yeasts, Burkholderia, monocots); please refer to the documentation of the distribution above.

Related papers

ANGES is based on the following papers:

• ANGES: reconstructing ANcestral GEnomeS maps. Bioinformatics, 28:2388-2390.
• A methodological framework for the reconstruction of contiguous regions of ancestral genomes and its application to mammalian genomes. PLoS Comput. Biol. 4:e1000234.
• Mapping ancestral genomes with massive gene loss: a matrix sandwich problem. ISMB/ECCB 2011, Bioinformatics 27:i257-i265.
• Yeast ancestral genome reconstructions: the possibilities of computation al methods II. J. Comput. Biol. 17:1097-1112.
• Tractability results for the Consecutive-Ones Property with multiplicity. CPM 2011, LNCS 6661:90-103.